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“Glucose Responsive Insulin” Will Not Improve the Lives of Type 1 Diabetics
February 19th, 2012
I spend time studying developments in diabetes research, and when possible I like to help other diabetes decision makers with my analysis. Today I am sharing a letter I sent to the president of Juvenile Diabetes Research Fund (JDRF), Jeffrey Brewer, explaining why I think their Glucose Responsive Insulin program is highly unlikely to produce [...]
Design Protocol for Large-Animal Islet Sheet Study
January 30th, 2012
My last posting marked the start of trials at the new Cedars-Sinai lab to determine the efficacy of the Islet Sheet in large mammals—a long-awaited goal. It also talked about Professor Richard Bergman’s vision for his new Diabetes and Obesity Research Institute there. The fact that Bergman, known as a leader in type 2 research, [...]
The Crucial Year for Islet Sheet is 2012
January 17th, 2012
A year ago I posted an article to this blog titled “The Crucial Year for Islet Sheet is 2011.” I was off by a year, as it turned out; last year was a transition year. The crucial year begins today. As I wrote last year, “The definitive experimental model is large animals (pig, dog, monkey) [...]
Advice for Paul of Michigan
January 2nd, 2012
Question: Hi Scott – my name is Paul B***** from Oxford, Michigan. I am a type 1 diabetic, diagnosed at age six. I am now studying Cell and Molecular Biology as an undergrad at Grand Valley State University. I was reading your work, and I’ve become fascinated with the idea of bioengineering and immunology. It’s [...]
Interview at JDCA Blog
December 23rd, 2011
The Juvenile Diabetes Cure Alliance sometimes features an interview with a type 1 diabetes researcher. Recently they published an interview of me discussing the Islet Sheet. Here is the text reproduced; for the original click the link. Scott King was diagnosed with type 1 diabetes in 1978. He worked as an investment analyst specializing in [...]
How Islet Autotransplantation Led to the Islet Sheet
December 12th, 2011
When I tell the story of the Islet Sheet these days, I find that I am emphasizing the importance of islet autotransplantation, or autografting. It’s success was the inspiration for the research that led to the Islet Sheet. The story in brief: The Islet Sheet is a second-generation islet encapsulation device intended to make the [...]
The Year of the Dog
November 27th, 2011
Welcome to our new website! It is a pleasure to resume this blog, now named The Sheet—for the Islet Sheet, of course. (It’s also journalism slang for a periodical.) This is an exciting time at Islet Sheet Medical. We have made an important addition to our team. VoxPop Films is making a documentary about our [...]
Farewell to The Solving Diabetes Project Web Site
September 27th, 2011
This is my final posting to this blog at the Solving Diabetes Project. My Islet Sheet Project blog will continue at a new URL in October. I am in the midst of consolidating our new three-way (or five-way) collaboration. We have achieved our technical goals in Islet Sheet fabrication and are ready to commence large [...]
Highlights of ADA Scientific Sessions III – What A1C for T2D?
August 15th, 2011
Here is my final post based on what I learned at the June ADA meeting. It was the final session I attended, titled: POST ACCORD – IS GLYCEMIA A MOVING TARGET? Three (clinically active) experts dissected the corpse of the ACCORD study. (Here is an overview; here is a discussion of the unexpected results.) These [...]
diaTribe Report: Targeting a Cure for Type 1 Diabetes
July 31st, 2011
“Targeting a Cure for Type 1 Diabetes” has been published on diaTribe by Kelly Close’s Close Concerns diabetes research organization. It is detailed, well considered, and makes room for personal opinions, observations and predictions. I recommend you download and read it, here. Our work on the Islet Sheet is described in page 67 in the [...]
